With the continuous promotion of the environmental protection industry, the problem of cleanliness in the pharmaceutical machine industry is getting more and more attention. However, the tablet presses currently used by most small and medium-sized pharmaceutical companies, due to the limitations and defects of the equipment, also give the company's GMP management and Product quality brings many practical problems. Such as pollution, cleaning difficulties, the product can not be achieved on-line detection, equipment operation records by manual fill. Therefore, how to break through these problems is a mechanical problem in the tablet press industry.
In recent years, due to the lack of awareness of energy conservation and environmental protection, tablet machine manufacturers are generally pursuing high speed, high output, and low prices in product design and manufacturing, and have not paid much attention to the modern management and GMP requirements of pharmaceutical companies.
One of the main reasons for the contamination of the tablet press is the unreasonable design of the lubrication system. It does not fully consider the peculiarities of the pharmaceutical equipment. A large number of equipment lubricants use liquid lubricants, combined with poor sealing, often causing drug contamination. Equipment manufacturers may consider adding time-lubricated lubricants on the tablet press or adopting reliable sealing methods to reduce or eliminate the contamination of lubricants with lubricants.
Another major source of contamination is the poor sealing of feeders and rotating platforms, causing dust pollution. British MANESTY adopts a gapless feeder with a polyurethane seal ring structure so that the gap between the bottom of the feeder and the die in the turntable can achieve zero clearance, thus avoiding the defects of the current feeder in sealing.
Most home-made tablet presses are very difficult to clean and cannot be cleaned online. Not only do you need to remove the upper punch, the lower punch, and the middle mold when cleaning, but there are also many dead angles that are not easily removable and difficult to clean. Some foreign presses can achieve rapid loading and unloading and online cleaning. That is, using a small number of tools and adjusting a small number of parts can quickly and easily install and remove parts that need to be cleaned. Some tablet presses also use a changeable table for quick cleaning. Domestic tablet presses should also be improved in this regard.
The tablet press industry should clearly understand the causes of the problems and then establish a correct concept of development. Start with energy saving and environmental protection, increase technical efforts, and constantly improve problems, so that the development of tablet presses continuously meet the needs of the industry.
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