The Importance of Cold Chain Transport to Vaccines - What Consequences Can Be Made Incorrectly?
Vaccine is a kind of medicine that contains pathogens by special treatment. It not only retains the features (antigenicity) that can be recognized by the immune system, but also destroys its lethality. In addition, the vaccine also contains some auxiliary ingredients, such as adjuvants, preservatives, stabilizers and so on. Therefore, there are very strict requirements for its transportation.
Due to the fact that vaccines are manufactured from the factory to the inoculation, they undergo many circulation, transportation, and storage processes, plus their sensitivity to temperature. Therefore, in order to ensure the stability and antigenicity of the vaccine, the whole cold chain is particularly important. In general, general liquid vaccines require 2 to 8°C refrigeration, and lyophilized vaccines require minus 20°C cryopreservation. In order to ensure the low temperature, many professional equipments are needed in the transportation and storage of vaccines, including low-temperature cold storage, ice chillers, ordinary cold storage, refrigerated trucks, refrigerators, and refrigerated backpacks.
In the cold chain transport of vaccines, transport vehicles and temperature monitoring systems are indispensable. Perfect hardware is the prerequisite to ensure that the vaccine is intact in the cold chain. To make a cold chain of vaccines, the most basic is to have excellent hardware equipment. Like refrigerated trucks, vehicles and chillers need to be strictly controlled to ensure that they are intact. This is the basis for the cold chain transport of vaccines. What are the implications of problems in the cold chain transportation?
First, it will cause the vaccine to fail because the antigen component of the vaccine will be inactivated under inappropriate storage conditions. Even if it is vaccinated, the body cannot produce immunity when it encounters pathogens, so it is also a fight.
Secondly, depending on the type of vaccines inoculated, as the over-temperature inactivated vaccines are as ineffective as counterfeit drugs, the consequences of inoculation are immeasurable, and serious deaths can result. Another point is that the effects of ineffective vaccines may not be obvious in a short time, but the long-term potential risks are immeasurable. When a large number of people are not immune to a disease or a variety of diseases, it is bound to greatly Increase the outbreak rate of the disease and the risk of epidemic.
Finally, ineffective vaccines may bring direct toxic and side effects. Although there are currently no case reports at home and abroad that directly result in injury or death due to inoculation of an over-temperature vaccine, we cannot fully rule out whether the over-temperature vaccine will bring The possibility of "direct toxic side effects".
The above is the fact that cold chain transportation plays an extremely important role in vaccines. Therefore, it reminds us that those who are engaged in vaccine transportation must be transported in accordance with the quasi-lateral regulations prescribed by the state. Because of carelessness, there will be incalculable consequences.
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